Senior Bioinformatics Engineer

Twist Bioscience synthesizes genes from scratch, providing precision DNA writing through their unique silicon-based DNA Synthesis Platform for healthcare, agriculture, industrial chemicals, and data storage.
$140,000 - $178,000
Backend
Senior Software Engineer
In-Person
5+ years of experience
Biotech · Healthcare

Description For Senior Bioinformatics Engineer

Twist Bioscience, a pioneering company in DNA synthesis, is seeking a Senior Bioinformatics Engineer to join their innovative team. This role represents a unique intersection of advanced software engineering and cutting-edge biotechnology, focusing on building robust infrastructure for processing next-generation sequencing (NGS) data.

The position offers an exciting opportunity to work at the forefront of biological research and development, where you'll be responsible for designing and implementing production-grade bioinformatics pipelines. You'll be working with state-of-the-art sequencing technologies and solving complex distributed systems challenges that directly impact the future of genomics research.

As a Senior Bioinformatics Engineer, you'll be instrumental in architecting cloud-native infrastructure for large-scale genomic data processing, implementing containerized workflows, and establishing best practices for the entire development lifecycle. The role requires a strong background in software engineering, with expertise in languages like Python and Rust, combined with proficiency in modern DevOps tools and cloud services.

The ideal candidate will bring at least 5 years of software engineering experience and a deep understanding of distributed systems. You'll be working in the San Francisco Bay Area, collaborating with a diverse team of scientists, bioinformaticians, and software engineers to translate complex research methods into production-ready solutions.

Twist Bioscience offers a competitive compensation package ranging from $140,000 to $178,000 USD, along with the opportunity to work on meaningful projects that advance biological research. The company's unique silicon-based DNA Synthesis Platform is helping to revolutionize fields such as healthcare, agriculture, industrial chemicals, and data storage.

This role is perfect for someone who is passionate about combining software engineering excellence with biological research, and who wants to be part of a company that's literally writing the future of DNA synthesis. You'll have the chance to make a significant impact while working with cutting-edge technologies in a collaborative and innovative environment.

Last updated 2 months ago

Responsibilities For Senior Bioinformatics Engineer

  • Design and implement production-grade bioinformatics pipelines for processing NGS data
  • Architect and maintain cloud-native infrastructure for large-scale genomic data processing
  • Build and optimize containerized bioinformatics workflows
  • Implement monitoring, alerting, and observability solutions
  • Develop and maintain CI/CD pipelines
  • Collaborate with scientists and engineers to translate research methods into production-ready solutions
  • Lead technical discussions and architectural decisions
  • Establish best practices for version control, testing, and deployment

Requirements For Senior Bioinformatics Engineer

Python
Rust
Linux
Kubernetes
Kafka
RabbitMQ
  • Minimum 5 years of software engineering experience with a Master's or equivalent
  • Advanced programming skills in Python, Rust, or C#
  • Proficient in Linux scripting
  • Experience with CI/CD tools including Git, Docker, Kubernetes
  • Strong experience with cloud environments and services (AWS)
  • Excellent written and verbal communication skills
  • MS/PhD in Bioinformatics, Computational Biology, or related field preferred
  • Experience with containerized workflows and event-driven architectures

Interested in this job?

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